Paediatric neuro-oncology is a specialized field focused on diagnosing and treating central nervous system (CNS) tumors in children, which are the most common solid tumors and leading cause of cancer mortality in this age group. Treatment requires a multidisciplinary approach, including surgery, radiation, and chemotherapy, with a focus on advanced, personalized care.
National Institutes of Health (NIH) | (.gov)
National Institutes of Health (NIH) | (.gov)
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Key Aspects of Paediatric Neuro-Oncology
Common Types: The most common pediatric brain tumors include astrocytomas (e.g., pilocytic astrocytoma) and medulloblastomas.
Diagnostic Techniques: Diagnosis heavily relies on advanced imaging and molecular characterization.
Treatment Modalities: While surgery is often the first step, treatment plans frequently involve radiation (including IMRT) and chemotherapy.
Symptoms: Signs can vary but often include persistent vomiting, headaches, balance issues, seizures, vision changes, and developmental regression.
Challenges: Some tumors, such as DIPG (diffuse intrinsic pontine gliomas), have high recurrence rates, and treatment can have significant long-term effects on quality of life.
Care Team: Specialized teams often include neuro-oncologists, neurosurgeons, and specialized nurses (nurse navigators).
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